WebbFör 1 dag sedan · The experimental results show that a high-fat diet can reduce the autophagy level of the liver in rats; intragastric administration of atorvastatin and ST36 grain-sized moxibustion stimulation can significantly increase the autophagy level of liver cells, while injection of Compound C inhibitor can affect the increase of autophagy level … Webb2 feb. 2024 · TBK1 belongs to the IKK-kinase family of kinases that are involved in innate immunity signaling pathways; specifically, TBK1 is an inducer of type-1 interferons. TBK1 also has a major role in autophagy …
Autophagy goes nuclear Nature Cell Biology
Webb11 apr. 2024 · A Comprehensive Review of Autophagy and Its Various Roles in Infectious, Non-Infectious, and Lifestyle Diseases: Current Knowledge and Prospects for Disease Prevention, Novel Drug Design, and Therapy. 2. Mansel, P. e tal (1990). Enhanced Thermogenic Response to Epinephrine After 48-Hour Starvation in Humans. 3. Zauner, C. … Webb13 jan. 2024 · Autophagy has also been linked to fibrosis [14, 15]. It was shown to promote fibroblast-to-myofibroblast differentiation through activation of the mechanistic target of rapamycin kinase complex 2 (MTORC2) [16, 17]. Studies on cross-talk between autophagy and senescence in fibroblasts show contradictory context-dependent results [18, 19]. charging bars
TBK1: a new player in ALS linking autophagy and …
Webb5 okt. 2024 · Autophagy is a highly conserved process that utilizes lysosomes to selectively degrade a variety of intracellular cargo, thus providing quality control over cellular components and maintaining cellular regulatory functions. Autophagy is triggered by multiple stimuli ranging from nutrient starvation to microbial infection. Webb25 dec. 2024 · Intersecting roles of ER stress, mitochondrial dysfunction, autophagy, and calcium homeostasis in HIV-associated Neurocognitive … WebbXian H, Yang S, Jin S, et al. LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I. Autophagy. 2024;16(3):408–418. 105. Tschurtschenthaler M, Adolph TE. The selective autophagy receptor optineurin in crohn’s disease. Front Immunol. 2024;9:766. 106. harris services byron ga