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WebLuminal Androgen Receptor Breast Cancers (LAR BCs) are characterized by a triple negative phenotype and by the expression of Androgen Receptor (AR), ... Androgen Receptor-Mediated Signaling Pathways in AR Positive TNBC. Structurally, AR comprises three functional domains: an N-terminal domain (NTD, residues 1–555), a DNA binding domain ... WebFeb 2, 2013 · Other work has further demonstrated that MUC1 translation is markedly upregulated in non-malignant breast epithelial cells in response to EGF or heregulin stimulation and activation of PI3K→AKT signaling. In breast cancer cells, MUC1 translation is constitutively upregulated by the PI3K→AKT→mTORC1 pathway and the eIF4A RNA … homes for rent in wayne nj
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