Pttg1ip knockout mouse
WebThe KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the … WebOct 27, 2024 · PTTG1IP promotes the shift of securin from the cell cytoplasm to the nucleus, allowing the interaction between separase and securin. PTTG1IP overexpression has been previously observed in malignant disease, e.g. in breast carcinoma. However, the prognostic value of PTTG1IP in breast carcinoma patients has not previously been revealed.
Pttg1ip knockout mouse
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WebNational Center for Biotechnology Information WebFeb 10, 2024 · A key finding supporting a causal role of the immune system in the pathogenesis of hypertension is the observation that RAG1 knockout mice on a C57Bl/6J background (B6.Rag1 −/ −), which lack functional B …
WebKnockout mouse. A knockout mouse, or knock-out mouse, is a genetically modified mouse ( Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene … WebThe benefits of using the knockout or knock-in mouse model to study disease include its endless applications and relative ease of manipulation. Knockout and Knock-in Technology Highlight: CRISPR/Cas9. Indeed, knockout and knock-in mouse models have been developed to both understand the mechanisms of diseases and discover drugs to treat them.
WebOct 27, 2024 · Pituitary tumour transforming gene 1 interacting protein (PTTG1IP, also PTTG1-binding factor, PBF) is an oncogene, originally detected as a 22 kDa protein binding to securin [1, 2].Securin, the protein product of PTTG1, in turn, is a proto-oncogene first described in rat pituitary tumour cells [].Both proteins are key actors in the complex … WebJan 1, 2008 · Description. Identified through its interaction with pituitary tumor transforming 1 (PTTG), the PTTG1IP protein is 180 amino acids long with a molecular mass of approximately 25 kDa. A putative signal peptide exists at the N-terminus (1-32). A domain of unknown function common to plexins, semaphorins and integrins (PSI) is located …
WebView mouse Pttg1ip Chr10:77417554-77434566 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression ... Deltagen and Lexicon …
WebPhenotype data for mouse gene Pttg1ip2. Discover Pttg1ip2's significant phenotypes, expression, images, histopathology and more. ... Phenotyping is currently not planned for a knockout strain of this gene. Gene Summary. Name: PTTG1IP family member 2. Synonyms: LOC381716, 1700015F17Rik. Order Alleles. IMPC Data Collections. No Body Weight Data bcg 英語 パンフレットWebOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach … 占いツクール ハイキュー マネージャー 愛されWebMar 21, 2024 · Complete information for PTTG1IP gene (Protein Coding), PTTG1 Interacting Protein, including: function, proteins, disorders, pathways, orthologs, and expression. … bcg 跡がないWebتعطيل الجين في الفأر bch200b300 マイクWebView mouse Pttg1ip2 Chr5:5487827-5529143 with: phenotypes, sequences, polymorphisms, proteins, references, function ... Deltagen and Lexicon Knockout Mice; International … bcg 集団接種 なぜWebOct 1, 2011 · Abstract. Pituitary tumor transforming gene (PTTG)-binding factor (PBF or PTTG1IP) is a little characterized proto-oncogene that has been implicated in the etiology of breast and thyroid tumors. In this study, we created a murine transgenic model to target PBF expression to the thyroid gland (PBF-Tg mice) and found that these mice exhibited ... bch200b300 パソコンWebPttg1ip - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. Pttg1ip Mouse Gene Knockout Kit (CRISPR), KN514250 AMSBIO The store will not work … bcg 服装 ノースリーブ