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WebJul 2, 2004 · We find that transmission of a suppressive signal by CD4CD25 + regulatory cells requires engagement of the B7 molecule expressed on target T cells. The response of T cells from B7-deficient mice is resistant to suppression in vitro, and these cells provoke a lethal wasting disease in lymphopenic mice despite the presence of regulatory T cells ... Web1. : the act of including : the state of being included. 2. : something that is included: such as. a. : a gaseous, liquid, or solid foreign body enclosed in a mass (as of a mineral) b. : a … günther hirth coswig
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