Webb8 juni 2024 · Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: Neurocognitive testing and biological imaging (HIPPORAD) - A phase II … WebbHIPPORAD-Study (NOA-14 / ARO 2015-3) Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (4 -10 brain metastases) Treatment arm A: Experimental intervention: HA-WBRT with concomitant boost to the metastases, total dose to whole brain (PTV=
PRO Ganzhirn: Indikation wann und mit welcher Technik?
WebbHA-WBRT patients were treated analogously to the ongoing HIPPORAD-trial (DRKS00004598) protocol with 30 Gy in 12 fractions and dose to 98% of the … Webb7 juni 2024 · This is a protocol of a randomized phase II trial designed to test a new strategy of WBRT for preventing cognitive decline and increasing tumor control in patients with multiple brain metastases. The HIPPORAD trial is registered with the German Clinical Trials Registry ( DRKS00004598 , registered 2 June 2016). b \u0026 q drumchapel glasgow
Advances in radiotherapy for brain metastases - Oxford Academic
Webb22 dec. 2015 · Overall, sparing of the hippocampi seems to be beneficial for patients undergoing WBRT. In Germany a prospective randomized multicenter phase II study is being launched (the HIPPORAD study) to investigate the neurocognitive outcome of patients with metastases receiving WBRT with hippocampal sparing and dose escalation . Webb8 juni 2024 · Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD) - a phase II prospective randomized multicenter trial (NOA-14, ARO 2015-3, DKTK-ROG). WebbBACKGROUND: The current study was aimed at investigating the feasibility of hippocampus-avoidance whole-brain radiation therapy with a simultaneous integrated boost (HA-WBRT+SIB) for metastases and at assessing tumor control in comparison with conventional whole-brain radiation therapy (WBRT) in patients with multiple brain … b \u0026 q dremel