Chemerin in atherosclerosis
WebJul 27, 2024 · Chemerin has been shown to be associated with inflammation and metabolic syndrome, which are in turn leading risk factors for atherosclerosis. A few clinical studies have concentrated on the role of chemerin in atherosclerosis but … Webkines resistin and chemerin play a proinflammatory role in atherosclerosis.10 Resistin is an important regulator of interactions between endothelial cells, macrophages, and vascular smooth muscle cells (SMC), in the develop-ment of atherosclerosis.11 Specifically, resistin increases the expression of proinflammatory markers (ie, mono-
Chemerin in atherosclerosis
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WebMar 23, 2024 · Chemerin also stimulates insulin-mediated glucose uptake and improves insulin action in 3T3-L1 adipocyte to treat obesity and insulin resistance (Takahashi et al., 2008). The present study highlights C. odorata and coumarin treated rats as presenting high levels of adiponectin and reduced levels of leptin and chemerin. ... atherosclerosis, ... WebChemerin promotes tumorigenesis by triggering the production and activity of matrix metalloproteinase, which plays a crucial role in angiogenesis, while the antitumor role for high chemerin levels has been reported to be through recruitment of natural killer (NK) cells which would help the immune system to recognize and fight the cancer cells ...
WebApr 30, 2014 · Depending on their anatomical location, different fat depots have a different capacity to produce bioactive peptides, called adipokines. Adipokines produced by … WebMay 22, 2024 · In this review, we will therefore highlight a selection of these receptors or receptor sub-families mainly expressed on myeloid cells and their role in atherosclerosis. More specifically, we will focus on chemokine receptors, both classical and atypical, formyl-peptide receptors, the chemerin receptor 23 and the calcium-sensing receptor.
WebJul 22, 2024 · Background: We previously reported that the adipokine chemerin, when added exogenously to the isolated rat mesenteric artery, amplified electrical field … WebOct 31, 2024 · Adipokine chemerin was known for its relationship with obesity as well as metabolism. Most recently, chemerin was found to play a crucial role in the pathologic process of cardiovascular diseases including coronary heart disease. In this study, we surveyed the role of chemerin in progression of atherosclerosis in ApoE−/− mice.
WebIn the aortas of atherosclerotic mice, chemerin expression was up-regulated compared to control mice. The plasma chemerin levels of CAD patients were higher than those of non-CAD patients (128.93 ± 37.06 vs. 109.85 ± 27.47 mmol/L, respectively, P < 0.001).
WebPurpose: Chemerin (RARRES2) is an endogenous leukocyte chemoattractant that recruits innate immune cells through its receptor, CMKLR1. ... For example, atherosclerosis, a chronic vascular disease ... harper ks to medicine lodge ksWebOct 31, 2024 · Adipokine chemerin was known for its relationship with obesity as well as metabolism. Most recently, chemerin was found to play a crucial role in the pathologic process of cardiovascular diseases including coronary heart disease. In this study, we surveyed the role of chemerin in progression of atherosclerosis in ApoE -/- mice. harper ks to chicago ilWebJul 23, 2024 · Gao et al found that the mRNA and protein expression levels of chemerin were significantly upregulated in epicardial adipose tissue from patients with CAD and the severity of coronary atherosclerosis was positively related to the chemerin expression. 10 In addition, Rodríguez‐Penas et al reported that chemerin was regulated by metabolic … characteristics of minicomputersWebMay 1, 2024 · Chemerin plays an important role in endothelial inflammation, as it induces monocyte-endothelial adhesion, a critical step in the development of atherosclerosis. … harper lace up shoesWebNov 18, 2024 · Chemerin’s association with the progression of atherosclerosis was investigated by manipulating chemerin levels in vivo. Adenovirus transfection was used to knockdown or overexpress the chemerin gene in the aorta or plasmacytoid dendritic cells (pDCs) of apolipoprotein (Apo) E −/− mice on a high-fat diet [ 173 , 174 ]. characteristics of minimalism in literatureWebMay 13, 2024 · Several studies have shown associations between circulating chemerin and carotid atherosclerosis. 9,32 The role of chemerin in atherosclerosis remains inconclusive with both proinflammatory and anti-inflammatory functions observed. 33 Chemerin can function as a chemoattractant for immune cells to the site of the plaque, ... characteristics of minicomputerWebChemerin promotes tumorigenesis by triggering the production and activity of matrix metalloproteinase, which plays a crucial role in angiogenesis, while the antitumor role for … harper lake baptist church